NewGyn - 1x2ml - Mastelli

NewGyn® is a class III injectable viscoelastic gel, developed by the Italian laboratory Mastelli, a pioneer in polynucleotide research for over 70 years. Designed to treat symptoms related to vulvovaginal atrophy, it combines polynucleotides and hyaluronic acid to regenerate and revitalize intimate tissues. 

Reserved for qualified physicians, NewGyn® offers a non-surgical clinical approach to sustainably improve the intimate well-being of patients.

Mode of action

NewGyn® activates fibroblasts, stimulates tissue regeneration, and promotes collagen synthesis. Hyaluronic acid maintains tissue hydration while mannitol protects and prolongs the activity of hyaluronic acid over time. 

The product acts at three levels simultaneously:

• Cell regeneration — PN-HPT® polynucleotides stimulate fibroblasts and accelerate tissue renewal
• Deep hydration — non-crosslinked hyaluronic acid restores the hydration of the mucosa
• Long-lasting protection — mannitol prolongs the activity of hyaluronic acid and reduces oxidative stress

Clinical indications

NewGyn® is indicated for women experiencing discomfort related to hormonal changes, childbirth, or aging. It effectively treats: 

• Vaginal dryness
• Itching and irritations
• Vulvar pain and dyspareunia
• Loss of tone and elasticity of the mucosa
• Vulvovaginal atrophy related to menopause

PN-HPT® Technology — The Mastelli Difference

Mastelli offers its patented technology of highly purified polynucleotides, known as PN-HPT® (High Purification Technology). The PN-HPT® are natural products derived from fish, obtained through a purification technology that ensures a high level of safety. 

Mastelli has complete control over its production chain and has conducted over 100 clinical studies, making it one of the most rigorous manufacturers in the polynucleotide market. 

Composition

Packaging & technical specifications

NewGyn® comes in a sterile pre-filled syringe of 2 ml with two 30G ½ needles. Class III medical device. 

• Volume: 2 ml per syringe
• Needles provided: 2 x 30G ½
• Injection depth: intradermal
• Technique: microdroplet, linear or fan-shaped
• Classification: Class III medical device — sterile viscoelastic gel

Recommended treatment protocol

The recommended protocol is one session every 14 to 21 days, for a total of 3 to 4 sessions. 

Results generally last between 6 and 12 months, depending on the individual patient's profile (skin type, age, hormonal balance). 

For which patient?

NewGyn® is particularly suitable for patients:

• In the perimenopausal or postmenopausal period
• Presenting with genitourinary atrophy (GSM syndrome)
• Having recently given birth with tissue laxity
• Seeking a non-hormonal alternative to local tritherapy

Regulatory information

This product is a class III medical device, reserved exclusively for authorized physicians. In accordance with decree no. 2024-490 of May 29, 2024, sales are strictly reserved for healthcare professionals holding a recognized medical degree.

We ship all orders from France with UPS, a guarantee of reliability.

📦 Processing Times

• Order prepared within 1 business day
• Shipping on the same day or the next day for orders confirmed before 12 PM.

🌍 Estimated Delivery Times

• France: 1 to 3 business days depending on the city
• Belgium: 1 to 2 business days
• Europe (EU): 1 to 4 business days, depending on the country
• Europe (Non-EU): 3 to 4 business days
• International (outside EU): 4 to 6 business days

We primarily work with UPS, if you wish to be delivered by another carrier, please contact us.

💰 Shipping Costs

• Free shipping for orders over €500 excluding tax
• Shipping costs calculated at the checkout based on your country.
• France: €10
• Europe: €20
• International: €45

🇮🇨 Shipments to the Canary Islands

Orders destined for the Canary Islands are processed only via WhatsApp.

• Fixed shipping fee: €35
• Please contact us directly to arrange your order and shipping.

🇺🇸 Shipments to the United States

For orders destined for the United States:

• Taxes are no longer applied on our site
• You will therefore pay no VAT at checkout
• However, customs and import fees may be charged by the carrier (UPS) upon arrival
• Fixed shipping fee: €45

👉 These fees are the responsibility of the customer and are independent of our service

🌍 Customs & Import Fees

For all orders outside the European Union:

• Customs fees, local taxes, and import fees are not covered by Hyashop
• These fees may be charged by the carrier upon delivery
• They remain entirely the responsibility of the customer

📍 Important Information

• A tracking number is sent after shipping
• In case of absence, the carrier may redirect the package to a pickup point
• Delivery times may be slightly affected during peak periods or holidays

💬 For any questions regarding your delivery, our customer service is available via WhatsApp or email.

At Hyashop, we take pride in providing responsive and professional customer service.

For any questions regarding our products, your orders, or delivery, our team is here to listen to you.

💬 For quick assistance, please contact us via WhatsApp.

📞 International

WhatsApp: +33 6 14 58 98 12

Email: contact@hyashop.com

📞 Spain

Phone & WhatsApp: +34 678 942 210

Email: ventas@hyashop.com

We remain at your disposal and will respond to you as soon as possible.

For hygiene reasons, products cannot be returned once opened.

A return is possible in case of a defective product, damaged item, or order error (within 48 hours).

👉 View the full return policy